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Adds confidence bands to a Kaplan Meier Estimate of Survival

Usage

stat_kmband(
  mapping = NULL,
  data = NULL,
  geom = "kmband",
  position = "identity",
  show.legend = NA,
  inherit.aes = TRUE,
  trans = "identity",
  firstx = 0,
  firsty = 1,
  type = "kaplan-meier",
  error = "greenwood",
  conf.type = "log",
  conf.lower = "usual",
  start.time = 0,
  conf.int = 0.95,
  ...
)

Arguments

mapping

Set of aesthetic mappings created by aes(). If specified and inherit.aes = TRUE (the default), it is combined with the default mapping at the top level of the plot. You must supply mapping if there is no plot mapping.

data

The data to be displayed in this layer. There are three options:

If NULL, the default, the data is inherited from the plot data as specified in the call to ggplot().

A data.frame, or other object, will override the plot data. All objects will be fortified to produce a data frame. See fortify() for which variables will be created.

A function will be called with a single argument, the plot data. The return value must be a data.frame, and will be used as the layer data. A function can be created from a formula (e.g. ~ head(.x, 10)).

geom

The geometric object to use to display the data for this layer. When using a stat_*() function to construct a layer, the geom argument can be used to override the default coupling between stats and geoms. The geom argument accepts the following:

  • A Geom ggproto subclass, for example GeomPoint.

  • A string naming the geom. To give the geom as a string, strip the function name of the geom_ prefix. For example, to use geom_point(), give the geom as "point".

  • For more information and other ways to specify the geom, see the layer geom documentation.

position

A position adjustment to use on the data for this layer. This can be used in various ways, including to prevent overplotting and improving the display. The position argument accepts the following:

  • The result of calling a position function, such as position_jitter(). This method allows for passing extra arguments to the position.

  • A string naming the position adjustment. To give the position as a string, strip the function name of the position_ prefix. For example, to use position_jitter(), give the position as "jitter".

  • For more information and other ways to specify the position, see the layer position documentation.

show.legend

logical. Should this layer be included in the legends? NA, the default, includes if any aesthetics are mapped. FALSE never includes, and TRUE always includes. It can also be a named logical vector to finely select the aesthetics to display.

inherit.aes

If FALSE, overrides the default aesthetics, rather than combining with them. This is most useful for helper functions that define both data and aesthetics and shouldn't inherit behaviour from the default plot specification, e.g. borders().

trans

Transformation to apply to the survival probabilities. Defaults to "identity". Other options include "event", "cumhaz", "cloglog", or define your own using scales::trans_new().

firstx, firsty

the starting point for the survival curves. By default, the plot program obeys tradition by having the plot start at (0,1).

type

an older argument that combined stype and ctype, now deprecated. Legal values were "kaplan-meier" which is equivalent to stype=1, ctype=1, "fleming-harrington" which is equivalent to stype=2, ctype=1, and "fh2" which is equivalent to stype=2, ctype=2.

error

either the string "greenwood" for the Greenwood formula or "tsiatis" for the Tsiatis formula, (only the first character is necessary). The default is "greenwood".

conf.type

One of "none", "plain", "log" (the default), "log-log" or "logit".

conf.lower

a character string to specify modified lower limits to the curve, the upper limit remains unchanged. Possible values are "usual" (unmodified), "peto", and "modified". The modified lower limit is based on an "effective n" argument. The confidence bands will agree with the usual calculation at each death time, but unlike the usual bands the confidence interval becomes wider at each censored observation. The extra width is obtained by multiplying the usual variance by a factor m/n, where n is the number currently at risk and m is the number at risk at the last death time. (The bands thus agree with the un-modified bands at each death time.) This is especially useful for survival curves with a long flat tail. The Peto lower limit is based on the same "effective n" argument as the modified limit, but also replaces the usual Greenwood variance term with a simple approximation. It is known to be conservative.

start.time

numeric value specifying a time to start calculating survival information. The resulting curve is the survival conditional on surviving to start.time.

conf.int

the level for a two-sided confidence interval on the survival curve(s). Default is 0.95.

...

Other arguments passed to survfit.formula

Value

a data.frame with additional columns:

x

x in data

ymin

Lower confidence limit of KM curve

ymax

Upper confidence limit of KM curve

Details

This stat is for computing the confidence intervals for the Kaplan-Meier survival estimate for right-censored data. It requires the aesthetic mapping x for the observation times and status which indicates the event status, 0=alive, 1=dead or 1/2 (2=death). Logical status is not supported.

Aesthetics

stat_kmband understands the following aesthetics (required aesthetics are in bold):

  • time The survival times

  • status The censoring indicator, see Surv for more information.

  • alpha

  • color

  • linetype

  • linewidth

Examples

library(ggplot2)
sex <- rbinom(250, 1, .5)
df <- data.frame(time = exp(rnorm(250, mean = sex)), status = rbinom(250, 1, .75), sex = sex)
ggplot(df, aes(time = time, status = status, color = factor(sex))) +
 stat_km()


## Examples illustrating the options passed to survfit.formula

p1 <- ggplot(df, aes(time = time, status = status))
p1 + stat_km() + stat_kmband(conf.int = .99)

p1 + stat_kmband(error = "greenwood",fill="red",alpha=0.2) +
 stat_kmband(error = "tsiatis",fill="blue",alpha=0.2)+ stat_km()

p1 + stat_km() + stat_kmband(conf.type = "log-log")+ stat_kmband(conf.type = "log")